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Anti-VE-Cadherin Antibody (6P223)
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Catalog No. TMAY-03165
Alias cadherin 5, type 2 (vascular endothelium)
Anti-VE-Cadherin Antibody (6P223) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (6P223) can be used in FCM.
Anti-VE-Cadherin Antibody (6P223)
Anti-VE-Cadherin Antibody (6P223)
😃Good
Catalog No. TMAY-03165Alias cadherin 5, type 2 (vascular endothelium)
Anti-VE-Cadherin Antibody (6P223) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (6P223) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-VE-Cadherin Antibody (6P223) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (6P223) can be used in FCM. |
| Alias | cadherin 5, type 2 (vascular endothelium) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6P223 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse CDH5(CD144) expression on bEnd.3 cells. Cells were stained with purified anti-Mouse CDH5(CD144), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse VE-Cadherin / CD144 / CDH5 (rM VE-Cadherin / CD144 / CDH5; TMPY-01237; NP_033998.2; Met1-Ala592). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis. |
| Conjucates | Unconjugated |
| Others Formats | APC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Mouse VE-Cadherin / CD144 / CDH5 Protein (TMPY-01237) |
| Antigen Species | Mouse |
| Biology Area | Hemangioblast Markers, Cardiac Stem Cell Markers |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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