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DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 2-4 weeks | |
500 mg | Inquiry | 2-4 weeks |
Description | DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Molecular Weight | 523.62 |
Formula | C29H37N3O6 |
Cas No. | 1255942-08-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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