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Anti-Her2/ERBB2 Antibody-PE (6Z596)
🥰Excellent
Catalog No. TMAY-00042P
Anti-Her2/ERBB2 Antibody-PE (6Z596) is a PE-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-PE (6Z596) can be used in FCM.
Anti-Her2/ERBB2 Antibody-PE (6Z596)
Anti-Her2/ERBB2 Antibody-PE (6Z596)
🥰Excellent
Catalog No. TMAY-00042P
Anti-Her2/ERBB2 Antibody-PE (6Z596) is a PE-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-PE (6Z596) can be used in FCM.
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Product Introduction
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Chemical Properties
| Description | Anti-Her2/ERBB2 Antibody-PE (6Z596) is a PE-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-PE (6Z596) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6Z596 |
| Reactivity | Human |
| Verified Activity | 1. Immunofluorescence staining of Human ErbB2 in MCF7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Human ErbB2 monoclonal antibody (PE-conjugated, 10 µg/ml) at 37°C 1 hour. Positive staining was localized to plasma membrane. 2. Analysis of anti-human ErbB2 on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with PE Rabbit anti-human ErbB2. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human ErbB2 / HER2 extracellular domain (rh ErbB2; TMPY-01137; NP_004439.2; Met 1-Thr 652) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| Research Background | Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/Biotin/FITC |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human ErbB2 protein (TMPY-01137) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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