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CGP 35348

Name: CGP 35348
Brand: TargetMol
SKU: T21793
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21793Cas No. 123690-79-9

CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.

CGP 35348

🥰Excellent

Catalog No. T21793Cas No. 123690-79-9

CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$44	In Stock	In Stock
5 mg	$98	In Stock	In Stock
10 mg	$163	In Stock	In Stock
25 mg	$328	In Stock	In Stock
50 mg	$529	In Stock	In Stock
100 mg	$793	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.
In vivo	In male Wistar rats, CGP 35348(100, 300, and 900 mg/kg) produced an increase in the duration of non-REM sleep and rapid eye movement (REM) sleep and reduced strongly spike-wave discharges[2].

Chemical Properties

Molecular Weight	225.22
Formula	C₈H₂₀NO₄P
Cas No.	123690-79-9
Smiles	C(P(CCCN)(=O)O)(OCC)OCC
Relative Density.	1.131g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 41.66 mg/mL (184.97 mM), Sonication is recommended.

DMSO: < 2.25 mg/mL (10 mM, insoluble or slightly soluble)

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	4.4401 mL	22.2005 mL	44.4010 mL	222.0052 mL
5 mM	0.8880 mL	4.4401 mL	8.8802 mL	44.4010 mL
10 mM	0.4440 mL	2.2201 mL	4.4401 mL	22.2005 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.2220 mL	1.1100 mL	2.2201 mL	11.1003 mL
50 mM	0.0888 mL	0.4440 mL	0.8880 mL	4.4401 mL
100 mM	0.0444 mL	0.2220 mL	0.4440 mL	2.2201 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc