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L-Praziquanamine

Name: L-Praziquanamine
Brand: TargetMol
SKU: T19400
Price: 69 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: (+)-Praziquanamine) Copy Product Info

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Synonyms: (+)-Praziquanamine

Catalog No. T19400 Copy Product Info

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L-Praziquanamine is a high-purity biochemical reagent used in biochemical experiments and pharmaceutical synthesis research.

Cas No. 99746-73-3

Pack Size	Price	USA Stock	Global Stock
2 mg	$30	-	In Stock
5 mg	$69	-	In Stock
10 mg	Preferential	-	In Stock
1 mL x 10 mM (in DMSO)	$69	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	L-Praziquanamine is a high-purity biochemical reagent used in biochemical experiments and pharmaceutical synthesis research.
In vitro	L-Praziquanamine, the enantiomer of praziquanamine, exhibits parasiticidal activity against Schistosoma spp., including Schistosoma japonicum. This compound disrupts calcium homeostasis (Ca(2+)), leading to muscle contraction, tegumental damage, and ultimately the death of the parasite. Therefore, L-Praziquanamine holds potential as a therapeutic agent for schistosomiasis treatment.
Synonyms	(+)-Praziquanamine

Chemical Properties

Molecular Weight	202.25
Formula	C₁₂H₁₄N₂O
Cas No.	99746-73-3
Smiles	O=C1N2[C@@](C=3C(CC2)=CC=CC3)(CNC1)[H]
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (395.55 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9444 mL	24.7219 mL	49.4438 mL	247.2188 mL
5 mM	0.9889 mL	4.9444 mL	9.8888 mL	49.4438 mL
10 mM	0.4944 mL	2.4722 mL	4.9444 mL	24.7219 mL
20 mM	0.2472 mL	1.2361 mL	2.4722 mL	12.3609 mL
50 mM	0.0989 mL	0.4944 mL	0.9889 mL	4.9444 mL
100 mM	0.0494 mL	0.2472 mL	0.4944 mL	2.4722 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PraziquanamineL-PraziquanamineLPraziquanamineL Praziquanamine

Related Tags: L-Praziquanamine chemical structure | L-Praziquanamine in vitro | L-Praziquanamine formula | L-Praziquanamine molecular weight