Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial increase in differentially expressed genes and promotes enhanced apoptosis in HCT116 cells [1].
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Description | JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial increase in differentially expressed genes and promotes enhanced apoptosis in HCT116 cells [1]. |
Molecular Weight | 940.18 |
Formula | C51H66FN7O7S |
CAS No. | 2669785-85-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JPS036 2669785-85-5 inhibitor inhibit