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Anti-Proteasome 20S LMP2 Antibody (3S23)
😃Good
Catalog No. TMAC-03440
Alias RING12 protein, RING12, RING 12, Really interesting new gene 12 protein, PSMB9, PSMB6i, PSMB 9, PSB9_HUMAN, Proteasome subunit beta-1i, Proteasome subunit beta type-9, Proteasome subunit beta type 9, Proteasome subunit beta 6i, Proteasome related gene 2, Proteasome chain 7, Proteasome catalytic subunit 1i, Proteasome beta 9 subunit, proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2), Proteasome (prosome macropain) subunit beta type 9, OTTHUMP00000062982, Multicatalytic endopeptidase complex chain 7, MGC70470, Macropain chain 7, Low molecular mass protein 2, LMP2, LMP 2, Large multifunctional protease 2, Large multifunctional peptidase 2, Beta1i
Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP.
Anti-Proteasome 20S LMP2 Antibody (3S23)
Anti-Proteasome 20S LMP2 Antibody (3S23)
😃Good
Catalog No. TMAC-03440Alias RING12 protein, RING12, RING 12, Really interesting new gene 12 protein, PSMB9, PSMB6i, PSMB 9, PSB9_HUMAN, Proteasome subunit beta-1i, Proteasome subunit beta type-9, Proteasome subunit beta type 9, Proteasome subunit beta 6i, Proteasome related gene 2, Proteasome chain 7, Proteasome catalytic subunit 1i, Proteasome beta 9 subunit, proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2), Proteasome (prosome macropain) subunit beta type 9, OTTHUMP00000062982, Multicatalytic endopeptidase complex chain 7, MGC70470, Macropain chain 7, Low molecular mass protein 2, LMP2, LMP 2, Large multifunctional protease 2, Large multifunctional peptidase 2, Beta1i
Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP. |
| Synonyms | RING12 protein, RING12, RING 12, Really interesting new gene 12 protein, PSMB9, PSMB6i, PSMB 9, PSB9_HUMAN, Proteasome subunit beta-1i, Proteasome subunit beta type-9, Proteasome subunit beta type 9, Proteasome subunit beta 6i, Proteasome related gene 2, Proteasome chain 7, Proteasome catalytic subunit 1i, Proteasome beta 9 subunit, proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2), Proteasome (prosome macropain) subunit beta type 9, OTTHUMP00000062982, Multicatalytic endopeptidase complex chain 7, MGC70470, Macropain chain 7, Low molecular mass protein 2, LMP2, LMP 2, Large multifunctional protease 2, Large multifunctional peptidase 2, Beta1i |
| Ig Type | IgG |
| Clone | 3S23 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of Proteasome 20S LMP2 on different lysates using anti-Proteasome 20S LMP2 antibody at 1/500 dilution. Positive control: Lane 1: Mouse spleen tissue, Lane 2: U937, Lane 2: Mouse colon tissue. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Proteasome 20S LMP2 antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of Daudi cells with Proteasome 20S LMP2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The eukaryotic multicatalytic proteinase complex, otherwise known as the proteasome, is present in both the nucleus and cytoplasm of cells and contains at least 15 nonidentical subunits, which form a highly ordered ring-shaped structure. The proteasome is involved in an ATP/Ubiquitin-dependent proteolytic pathway and expresses at least five distinct proteolytic activities, including the cleavage of peptides after branched chain amino acids or bulky hydrophobic amino acids. Two components of the proteasome are the low molecular mass proteins LMP2 and LMP7, which are thought to connect the proteasome to the MHC class-I antigen-processing pathway. Upon stimulation with IFN-γ, LMP2 and LMP7 displace housekeeping subunits in the proteasome and activate cytotoxic T cells (CTLs). LMP2 and LMP7 are produced as precursor proteins, which are processed to subunits that have the ability to complex with the proteasome. LMP2 is expressed as two alternatively spliced forms, LMP2.l and LMP2.s, in lymphoblastoid cell lines and in fibroblasts after IFN-γ stimulation. LMP7 is also expressed as two forms, LMP7-E1 and E2, in several tissues. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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