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Anti-Proteasome 20S LMP2 Antibody (3S23)

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Catalog No. TMAC-03440

Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP.

Anti-Proteasome 20S LMP2 Antibody (3S23)

Anti-Proteasome 20S LMP2 Antibody (3S23)

😃Good
Catalog No. TMAC-03440
Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Proteasome 20S LMP2 Antibody (3S23) is a Rabbit antibody targeting Proteasome 20S LMP2. Anti-Proteasome 20S LMP2 Antibody (3S23) can be used in WB,IHC,FCM,IP.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe eukaryotic multicatalytic proteinase complex, otherwise known as the proteasome, is present in both the nucleus and cytoplasm of cells and contains at least 15 nonidentical subunits, which form a highly ordered ring-shaped structure. The proteasome is involved in an ATP/Ubiquitin-dependent proteolytic pathway and expresses at least five distinct proteolytic activities, including the cleavage of peptides after branched chain amino acids or bulky hydrophobic amino acids. Two components of the proteasome are the low molecular mass proteins LMP2 and LMP7, which are thought to connect the proteasome to the MHC class-I antigen-processing pathway. Upon stimulation with IFN-γ, LMP2 and LMP7 displace housekeeping subunits in the proteasome and activate cytotoxic T cells (CTLs). LMP2 and LMP7 are produced as precursor proteins, which are processed to subunits that have the ability to complex with the proteasome. LMP2 is expressed as two alternatively spliced forms, LMP2.l and LMP2.s, in lymphoblastoid cell lines and in fibroblasts after IFN-γ stimulation. LMP7 is also expressed as two forms, LMP7-E1 and E2, in several tissues.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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