Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Enpp-1-IN-14 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1.Enpp-1-IN-14 has anti-tumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 672.00 | |
100 mg | In stock | $ 956.00 | |
1 mL * 5 mM (in DMSO) | In stock | $ 133.00 |
Description | Enpp-1-IN-14 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity. |
In vivo | Enpp-1-IN-14 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth in Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells). |
Molecular Weight | 403.88 |
Formula | C15H22ClN5O4S |
CAS No. | 2687222-59-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.33 mg/mL (8.25 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Enpp-1-IN-14 2687222-59-7 Metabolism PDE inhibitor inhibit