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Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2
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Catalog No. TMAC-00538
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII alpha/beta/gamma (Thr305). Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody can be used in WB,IHC,IF.
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-00538
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII alpha/beta/gamma (Thr305). Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody can be used in WB,IHC,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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| Description | Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII alpha/beta/gamma (Thr305). Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody can be used in WB,IHC,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:100-300; IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human CaMK2 alpha/beta/delta around the phosphorylation site of Thr305 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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