Liproxstatin-1 hydrochloride

Name: Liproxstatin-1 hydrochloride
Brand: TargetMol
SKU: T61567
Rating: 4.5 (1 reviews)

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Catalog No. T61567Cas No. 2250025-95-5

Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].

Liproxstatin-1 hydrochloride

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Catalog No. T61567Cas No. 2250025-95-5

Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].

Pack Size	Price	Availability	Quantity
5 mg	$383	35 days

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Product Introduction

Bioactivity

Description	Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].
In vitro	Liproxstatin-1 exhibits antiferroptotic effects, demonstrating an inhibitory concentration (IC 50) around 38 nM in mouse embryonic fibroblasts [2].
In vivo	Liproxstatin-1, administered intraperitoneally at a dosage of 10 mg/kg, effectively inhibits ferroptosis in human cells, Gpx4-deficient kidneys, and in a model of tissue injury induced by ischemia/reperfusion [1].

Chemical Properties

Molecular Weight	377.31
Formula	C₁₉H₂₂Cl₂N₄
Cas No.	2250025-95-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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