(+)-Nipecotic acid

Name: (+)-Nipecotic acid
Brand: TargetMol
SKU: T20114
Price: 1520 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20114Cas No. 59045-82-8

Alias (+)-β-Homoproline, (+)-Hexahydronicotinic acid, (+)-3-Carboxypiperidine)

(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors and elevating endogenous GABA concentrations, suitable for psychiatric disorder research.

(+)-Nipecotic acid

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Purity: 99.38%

Catalog No. T20114Alias (+)-β-Homoproline, (+)-Hexahydronicotinic acid, (+)-3-Carboxypiperidine)Cas No. 59045-82-8

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	-	In Stock
50 mg	$1,980	-	In Stock
100 mg	$2,500	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.38%

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Product Introduction

Bioactivity

Description	(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors and elevating endogenous GABA concentrations, suitable for psychiatric disorder research.
Synonyms	(+)-β-Homoproline, (+)-Hexahydronicotinic acid, (+)-3-Carboxypiperidine)

Chemical Properties

Molecular Weight	129.16
Formula	C₆H₁₁NO₂
Cas No.	59045-82-8
Smiles	C(O)(=O)[C@H]1CCCNC1
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc