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Anti-HER4/ERBB4 Antibody (2P920)
😃Good
Catalog No. TMAY-03534
Alias p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD
Anti-HER4/ERBB4 Antibody (2P920) is a Rabbit antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (2P920) can be used in ELISA.
Anti-HER4/ERBB4 Antibody (2P920)
Anti-HER4/ERBB4 Antibody (2P920)
😃Good
Catalog No. TMAY-03534Alias p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD
Anti-HER4/ERBB4 Antibody (2P920) is a Rabbit antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (2P920) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-HER4/ERBB4 Antibody (2P920) is a Rabbit antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (2P920) can be used in ELISA. |
| Alias | p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2P920 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ErbB4 / HER4 (rM ErbB4 / HER4; TMPY-03021; Q99P91; Met1-Leu652). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. And lower levels in thymus, lung, salivary gland, and pancreas. It specifically binds to and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. ERBB4 also can be activated by other factors and induces a variety of cellular responses including mitogenesis and differentiation. ERBB4 regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. It is required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. ERBB4 also play a role on the normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. It is required for mammary gland differentiation, induction of milk proteins and lactation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse ErbB4 / HER4 Protein (TMPY-03021) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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