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Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is P43489.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $91 | 7-10 days | |
| 10 μg | $148 | 7-10 days | |
| 20 μg | $245 | 7-10 days | |
| 50 μg | $483 | 7-10 days | |
| 100 μg | $813 | 7-10 days | |
| 200 μg | $1,470 | 7-10 days | |
| 500 μg | $3,250 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is P43489. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P43489 |
| Synonyms | TNFRSF4,OX40L receptor,OX40 homologue,OX40,Ly-70,IMD16,CD134,ACT-135, TXGP1L |
| Construction | Leu29-Ala216 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Molecular Weight | 46.8 kDa (predicted). Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |

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