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PPARα agonist4 (compound BH400) is a PPARα agonist with an EC50 of 1.2 μM. In addition to its primary activity, PPARα agonist4 inhibits STING with an IC50 of 8.1 μM. It also reduces reactive oxygen species production induced by CoCl2 and decreases IL-6 secretion prompted by LPS. Further, PPARα agonist4 restores the decreased expression of PCG1α caused by LPS.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder | 
| Description | PPARα agonist4 (compound BH400) is a PPARα agonist with an EC50 of 1.2 μM. In addition to its primary activity, PPARα agonist4 inhibits STING with an IC50 of 8.1 μM. It also reduces reactive oxygen species production induced by CoCl2 and decreases IL-6 secretion prompted by LPS. Further, PPARα agonist4 restores the decreased expression of PCG1α caused by LPS. | 
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | 
 For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL .
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL .  A total of 10 animals were administered, and the formula you used is 5%
 A total of 10 animals were administered, and the formula you used is 5%  DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。 (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
 (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first. main solution, add 300 μLPEG300
 main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O
 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
 mix well and clarify
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