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Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200)

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Catalog No. TMAC-03232

Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) is a Rabbit antibody targeting Phospho-JNK1/2/MAPK10 (T183/T183/T221). Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200)

Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200)

😃Good
Catalog No. TMAC-03232
Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) is a Rabbit antibody targeting Phospho-JNK1/2/MAPK10 (T183/T183/T221). Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) is a Rabbit antibody targeting Phospho-JNK1/2/MAPK10 (T183/T183/T221). Anti-Phospho-JNK1/2/MAPK10 (T183/T183/T221) Antibody (7N200) can be used in WB,ICC/IF,IHC,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundJNKs (c-Jun N-terminal kinases) belong to a family of MAP kinases that are involved in a variety of cellular processes, including transcriptional regulation and cellular proliferation, differentiation and development. JNK2 (c-Jun N-terminal kinase 2) and JNK3 (c-Jun N-terminal kinase 3) are 424 and 464 amino acid proteins, respectively, that each contain one protein kinase domain and use magnesium as a cofactor to catalyze the phosphorylation of target proteins, thereby playing a role in a variety of events throughout the cell. Both JNK2 and JNK3 exist as multiple alternatively spliced isoforms and are subject to post-translational phosphorylation on Thr 183 and Thr 221, respectively, an event which activates JNK2/JNK3 enzymatic activity. Defects in the gene encoding JNK3 are a cause of epileptic encephalopathy of the Lennox-Gastaut type, a group of epileptic disorders characterized by severe psychomotor delay and seizures.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human JNK1/2/3 around the phosphorylation site of Thr183 + Thr183 + Thr221
Antigen Species
human
Chemical Properties
Molecular WeightTheoretical: 54/46 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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