Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Angustifoline

😃Good
Catalog No. TN6547Cas No. 550-43-6

Angustifoline is a natural alkaloid isolated from Lupinus angustifolius L., exhibiting antimicrobial and anticancer properties. It inhibits the growth of various bacteria(S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis) and induces autophagy and apoptosis in human colon cancer cells.

Angustifoline
Other Forms of Angustifoline:
Angustifoline hydrochlorideT75439133398-34-2
Backorder
View details

Angustifoline

😃Good
Catalog No. TN6547Cas No. 550-43-6
Angustifoline is a natural alkaloid isolated from Lupinus angustifolius L., exhibiting antimicrobial and anticancer properties. It inhibits the growth of various bacteria(S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis) and induces autophagy and apoptosis in human colon cancer cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$1,268InquiryInquiry
1 mL x 10 mM (in DMSO)$1,389InquiryInquiry
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

COA

Product Introduction

Bioactivity
Description
Angustifoline is a natural alkaloid isolated from Lupinus angustifolius L., exhibiting antimicrobial and anticancer properties. It inhibits the growth of various bacteria(S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis) and induces autophagy and apoptosis in human colon cancer cells.
In vitro
Methods: Feeding inhibition was found in the alkaloid fraction of L. polyphyllus extracts. Eight lupin alkaloids present in the extracts were tested at a rate of 25 μg per feeding disk.
Results: Among these compounds, 13-trans-cinnamoyloxylupanine and 13-tigloyloxylupanine showed strong inhibitory effects, while lupine, galactoline, 13-hydroxylupine, tetrahydrolupine, Angustifoline, and 17-oxolupanine showed no inhibitory effects. Four alkaloids not present in L. polyphyllus, namely lupine, epilupine, α-isolupine, and lupinyl trans-cinnamate, were inactive at 25 μg per feeding disk.
Chemical Properties
Molecular Weight234.34
FormulaC14H22N2O
Cas No.550-43-6
SmilesO=C1N2[C@@]([C@]3(C[C@@](C2)([C@H](CC=C)NC3)[H])[H])(CCC1)[H]
Relative Density.1.10 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Angustifoline
Related Tags: buy Angustifoline | purchase Angustifoline | Angustifoline cost | order Angustifoline | Angustifoline chemical structure | Angustifoline in vitro | Angustifoline formula | Angustifoline molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.