IGF2/IGF-II Protein, Human, Recombinant (E. coli)

Name: IGF2/IGF-II Protein, Human, Recombinant (E. coli)
Brand: TargetMol
SKU: TMPS-00170
Rating: 4.5 (1 reviews)

(Synonyms: Somatamedin A, Insulin-like Growth Factor-II) Copy Product Info

Synonyms: Somatamedin A, Insulin-like Growth Factor-II

Catalog No. TMPS-00170 Copy Product Info

IGF2/IGF-II Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is P01344-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$54	7-10 days	7-10 days
10 µg	$85	-	In Stock
20 µg	$113	7-10 days	7-10 days
50 µg	$170	-	In Stock
100 µg	$268	7-10 days	7-10 days
200 µg	$426	7-10 days	7-10 days
500 µg	$792	7-10 days	7-10 days
1 mg	$1,270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Solid

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 20.0 ng/ml, measured by a cell proliferation assay using FDCP-1 cells, corresponding to a specific activity of > 5.0 × 10 4 units/mg.
Description	IGF2/IGF-II Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is P01344-1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P01344-1
Construction	Ala25-Glu91
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized after extensive dialysis against 25 mM Tris, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Somatamedin A, Insulin-like Growth Factor-II
Research Background	Insulin-like Growth Factor II (IGF-II) is a single chain 7 kDa polypeptide, and shares a high degree of homology with insulin. During circulation in vivo, IGF-II is complexed to high affinity binding proteins, IGF Binding Proteins (IGFBP), which act as circulating reservoirs, transport IGF-II, and prolong the half life of IGF-II. The receptors of IGF-II (IGFRs) are transmembrane tyrosine receptors, and are heterotetrameric consisting of two α-subunits and two β-subunits. IGFRs execute their role via intracellullar signaling molecules, such as IRS, shc, and PI3K. The functions of IGF-II include promoting cell survival, growth, proliferation, differentiation and motility. In particular, IGF-II promotes proliferation, inhibits death, and stimulates transformation in breast cancer cells.

Chemical Properties

Molecular Weight

~7.6 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Related Tags: IGF2/IGF-II Protein, Human, Recombinant (E. coli) chemical structure | IGF2/IGF-II Protein, Human, Recombinant (E. coli) molecular weight