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APRIL/TNFSF13 Trimer Protein, Mouse, Recombinant (hFc)
(Synonyms: Trdl1, Tnlg7b, Tnfsf13, Tall2, April, 2310026N09Rik) Copy Product InfoSynonyms: Trdl1, Tnlg7b, Tnfsf13, Tall2, April, 2310026N09Rik
Catalog No. TMPY-07211 Copy Product Info
APRIL/TNFSF13 Trimer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9D777.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $63 | 7-10 days | 7-10 days | |
| 10 µg | $98 | 7-10 days | 7-10 days | |
| 20 µg | $163 | 7-10 days | 7-10 days | |
| 50 µg | $323 | 7-10 days | 7-10 days | |
| 100 µg | $625 | 7-10 days | 7-10 days | |
| 200 µg | $939 | 7-10 days | 7-10 days | |
| 500 µg | $1,970 | 7-10 days | 7-10 days | |
| 1 mg | $3,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Recombinant Mouse APRIL/TNFSF13 Protein (Fc Tag) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse BCMA Protein (Fc & AVI Tag), Biotinylated, the EC50 is 2-6 ng/mL. |
| Description | APRIL/TNFSF13 Trimer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9D777. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | N-hFc |
| Accession Number | Q9D777 |
| Construction | A DNA sequence encoding the Mouse TNFSF13 (Q9D777) (Lys104-Leu241) was fused with the Fc region of human IgG1 at the N-terminus. This construct has a trimer design. |
| Protein Purity | ≥ 95% as determined by SDS-PAGE. ≥ 90% as determined by SEC-MALS(Routinely tested). |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile 50 mM Tris, 100 mM Glycine, 200 mM Arginine, 150 mM NaCl, 10% Trehalose, pH 7.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Synonyms | Trdl1, Tnlg7b, Tnfsf13, Tall2, April, 2310026N09Rik |
| Research Background | TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA. TNFSF13 is lowly expressed in normal tissues, but is elevated in several types of tumors and transformed cell lines. It is important for B cell development. TNFSF13 may also play a role in T-independent type II antigen responses and T cell survival, and induce proliferation/survival of non lymphoid cells. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. TNFSF13 also has been demonstrated to bind to proteoglycans on the cell surface. |
| Molecular Weight | 75.8 kDa (predicted); 80.1 kDa (reducing contition); 178.2 kDa (SEC-MALS) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: APRIL/TNFSF13 Trimer Protein, Mouse, Recombinant (hFc) chemical structure | APRIL/TNFSF13 Trimer Protein, Mouse, Recombinant (hFc) molecular weight
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