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RdRP-IN-2

🥰Excellent
Catalog No. T9617

RdRP-IN-2 is an RNA-dependent RNA polymerase (RdRp) inhibitor that significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM and also inhibits Feline coronavirus (FIPV) replication.

RdRP-IN-2

RdRP-IN-2

🥰Excellent
Purity: 99.54%
Catalog No. T9617
RdRP-IN-2 is an RNA-dependent RNA polymerase (RdRp) inhibitor that significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM and also inhibits Feline coronavirus (FIPV) replication.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30-In Stock
5 mg$67-In Stock
10 mg$115-In Stock
25 mg$243-In Stock
50 mg$392-In Stock
100 mg$629-In Stock
200 mg$886-In Stock
1 mL x 10 mM (in DMSO)$83-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.54%
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Product Introduction

Bioactivity
Description
RdRP-IN-2 is an RNA-dependent RNA polymerase (RdRp) inhibitor that significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM and also inhibits Feline coronavirus (FIPV) replication.
Targets&IC50
RdRps (SARS CoV-2):41.2 µM
Chemical Properties
Molecular Weight566.67
FormulaC33H30N2O5S
SmilesO=C1N2C3=CC(OC4CCCCC4)=CC=C3SC2=C(C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)C=C1C6=CC=CC=C6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (176.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7647 mL8.8235 mL17.6470 mL88.2348 mL
5 mM0.3529 mL1.7647 mL3.5294 mL17.6470 mL
10 mM0.1765 mL0.8823 mL1.7647 mL8.8235 mL
20 mM0.0882 mL0.4412 mL0.8823 mL4.4117 mL
50 mM0.0353 mL0.1765 mL0.3529 mL1.7647 mL
100 mM0.0176 mL0.0882 mL0.1765 mL0.8823 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SARS-CoV-2SARSCoVRdRP-IN-2RdRPIN2RdRP IN 2
Related Tags: buy RdRP-IN-2 | purchase RdRP-IN-2 | RdRP-IN-2 cost | order RdRP-IN-2 | RdRP-IN-2 chemical structure | RdRP-IN-2 formula | RdRP-IN-2 molecular weight
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