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Anti-Serotonin transporter Polyclonal Antibody

(Synonyms: Solute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter) Copy Product Info
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Synonyms: Solute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter

Catalog No. TMAB-01678 Copy Product Info
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Anti-Serotonin transporter Polyclonal Antibody is a Rabbit antibody targeting Serotonin transporter. Anti-Serotonin transporter Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Anti-Serotonin transporter Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Serotonin transporter Polyclonal Antibody is a Rabbit antibody targeting Serotonin transporter. Anti-Serotonin transporter Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
SynonymsSolute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Sheep,GuineaPig)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in platelets (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 5-HTT
Antigen Species
Human
Gene Name
SLC6A4
Gene ID
Protein Name
Sodium-dependent serotonin transporter
Uniprot ID
Biology Area
Drug metabolism,Sodium Channels,Serotonin / 5HT,Transporters,Drug metabolism
Function
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Chemical Properties
Molecular WeightTheoretical: 70 kDa. Actual: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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