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Anti-Serotonin transporter Polyclonal Antibody

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Catalog No. TMAB-01678
Alias Solute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter

Anti-Serotonin transporter Polyclonal Antibody is a Rabbit antibody targeting Serotonin transporter. Anti-Serotonin transporter Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Serotonin transporter Polyclonal Antibody

Anti-Serotonin transporter Polyclonal Antibody

😃Good
Catalog No. TMAB-01678Alias Solute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter
Anti-Serotonin transporter Polyclonal Antibody is a Rabbit antibody targeting Serotonin transporter. Anti-Serotonin transporter Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3737-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-Serotonin transporter Polyclonal Antibody is a Rabbit antibody targeting Serotonin transporter. Anti-Serotonin transporter Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
AliasSolute carrier family 6 member 4, Sodium dependent serotonin transporter, SLC6A4, SERT1, SERT, SC6A4, OCD1, Na+/Cl-dependent serotonin transporter, HTT, hSERT, 5-hydroxytryptamine transporter, 5-HTTLPR, 5-HTT, 5HTT, 5HT transporter
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Sheep,GuineaPig)
Verified Activity
1. Sample:
Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-SLC6A4 (TMAB-01678) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kDa
Observed band size: 70 kDa
2. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (Serotonin transporter) Polyclonal Antibody, Unconjugated (TMAB-01678) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (Serotonin transporter) Polyclonal Antibody, Unconjugated (TMAB-01678) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
Application
WB,IHC-P,IHC-Fr,IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 5-HTT
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Drug metabolism,Sodium Channels,Serotonin / 5HT,Transporters,Drug metabolism
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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