Shopping Cart

Your shopping cart is currently empty

Sodium Nitroprusside

Name: Sodium Nitroprusside
Brand: TargetMol
SKU: T0003
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0003Cas No. 14402-89-2

Alias Sodium Nitroferricyanide, Ro 21-2498, Nitroprusside Sodium

Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.

Sodium Nitroprusside

🥰Excellent

Catalog No. T0003Alias Sodium Nitroferricyanide, Ro 21-2498, Nitroprusside SodiumCas No. 14402-89-2

Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$40	In Stock	In Stock
100 mg	$50	In Stock	In Stock
200 mg	$67	In Stock	In Stock
500 mg	$87	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Appearance:Solid

Color:Red

Resource Download

COA

Product Introduction

Bioactivity

Description	Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.
In vitro	Administering 5 mg/kg of sodium nitroprusside, acting as a nitric oxide donor, effectively mitigates intestinal ischemia-reperfusion injury in rats.
In vivo	Sodium nitroprusside inhibits the proliferation of vascular smooth muscle. As an effective vasodilator, it exhibits pronounced dilation effects particularly in the arterioles and venules. During circulation, sodium nitroprusside decomposes to release nitric oxide (NO), which activates guanylate cyclase in vascular smooth muscle and augments intracellular cyclic guanosine monophosphate (cGMP) production, promoting the relaxation of the smooth muscle and consequent vasodilation.
Synonyms	Sodium Nitroferricyanide, Ro 21-2498, Nitroprusside Sodium

Chemical Properties

Molecular Weight	261.92
Formula	Na₂Fe(CN)5NO
Cas No.	14402-89-2
Smiles	[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
Relative Density.	1.72 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (381.8 mM), Sonication is recommended.

DMSO: 55 mg/mL (209.99 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.64 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.8180 mL	19.0898 mL	38.1796 mL	190.8980 mL
5 mM	0.7636 mL	3.8180 mL	7.6359 mL	38.1796 mL
10 mM	0.3818 mL	1.9090 mL	3.8180 mL	19.0898 mL
20 mM	0.1909 mL	0.9545 mL	1.9090 mL	9.5449 mL
50 mM	0.0764 mL	0.3818 mL	0.7636 mL	3.8180 mL
100 mM	0.0382 mL	0.1909 mL	0.3818 mL	1.9090 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc