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SPF30 Protein, Human, Recombinant (His)

(Synonyms: TDRD16C, survival motor neuron domain containing 1, SPF30, SMNR) Copy Product Info

Synonyms: TDRD16C, survival motor neuron domain containing 1, SPF30, SMNR

Catalog No. TMPY-03451 Copy Product Info
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis.
SPF30 Protein, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$797-10 days7-10 days
10 μg$1297-10 days7-10 days
20 μg$2087-10 days7-10 days
50 μg$4197-10 days7-10 days
100 μg$8127-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis.
Species
Human
Expression System
E. coli
TagN-His
Accession NumberO75940
ConstructionA DNA sequence encoding the mature form of human SMNDC1 (O75940) (Met1-Gln238) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His
Protein Purity
> 85 % as determined by SDS-PAGE
EndotoxinPlease contact us for more information.
FormulationSupplied as sterile PBS, 20% Glycerol, pH 7.4.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageIt is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsTDRD16C, survival motor neuron domain containing 1, SPF30, SMNR
Research Background
Chemical Properties
Molecular Weight28.5 kDa (predicted); 29 kDa (reducing conditions)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: SPF30 Protein, Human, Recombinant (His) chemical structure | SPF30 Protein, Human, Recombinant (His) molecular weight