store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autophagy and promotes intracellular mitochondrial regeneration.TSPO ligand-1 is involved in intracellular cholesterol transport, and can be used as a biomarker for brain injury and neurodegeneration. TSPO ligand-1 is involved in intracellular cholesterol transport and can be used as a biomarker for brain damage and neurodegeneration.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 71.00 | |
10 mg | In stock | $ 118.00 | |
25 mg | In stock | $ 237.00 | |
50 mg | In stock | $ 355.00 | |
100 mg | In stock | $ 533.00 | |
500 mg | In stock | $ 1,130.00 |
Description | TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autophagy and promotes intracellular mitochondrial regeneration.TSPO ligand-1 is involved in intracellular cholesterol transport, and can be used as a biomarker for brain injury and neurodegeneration. TSPO ligand-1 is involved in intracellular cholesterol transport and can be used as a biomarker for brain damage and neurodegeneration. |
In vitro |
In the context of selective activation of neurons in male C57Bl6/N mice, the TSPO ligand-1 gene is induced to increase expression. Additionally, under both physiological and psychopharmacological conditions, neuronal activation leads to increased TSPO levels in adult mice[2]. As the sole marker of glial cell activity in Alzheimer’s disease, TSPO ligand-1 can track the formation of different neural cells[4]. In the MA-10 Leydig cell line, TSPO ligand-1 can regulate mitochondrial fatty acid oxidation (FAO) and thus affects mitochondrial energy homeostasis[3]. |
Molecular Weight | 283.71 |
Formula | C16H10ClNO2 |
CAS No. | 4560-08-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (176.24 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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TSPO ligand-1 4560-08-1 Autophagy inhibitor inhibit