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Anti-MCP-1/CCL2 Polyclonal Antibody 2 is a Rabbit antibody targeting MCP-1/CCL2. Anti-MCP-1/CCL2 Polyclonal Antibody 2 can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Antibody Type: Rabbit Polyclonal Application: WB,ELISA Reactivity: Mouse,Rat (predicted:Human) |
Ig Type | IgG |
Reactivity | Mouse,Rat (predicted:Human) |
Verified Activity | Sample: Lane 1: Lung (Mouse) Lysate at 40 μg Lane 2: Spleen (Mouse) Lysate at 40 μg Lane 3: LympHnode (Mouse) Lysate at 40 μg Lane 4: Lung (Rat) Lysate at 40 μg Lane 5: Spleen (Rat) Lysate at 40 μg Lane 6: LympHnode (Rat) Lysate at 40 μg Primary: Anti-MCP1 (TMAB-01116) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 11 kDa Observed band size: 11 kDa |
Application | WB,ELISA |
Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside. |
Immunogen | KLH conjugated synthetic peptide: human MCP-1 |
Antigen Species | Human |
Gene ID | 6347 |
Uniprot ID | |
Biology Area | Response to hypoxia,Chemokines,Alpha Chemokines (CXC),Hypoxia,Heart disease |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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