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Anti-NQO1 Antibody (2T646)
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Catalog No. TMAY-02207
Alias QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU
Anti-NQO1 Antibody (2T646) is a Rabbit antibody targeting NQO1. Anti-NQO1 Antibody (2T646) can be used in WB.
Anti-NQO1 Antibody (2T646)
Anti-NQO1 Antibody (2T646)
😃Good
Catalog No. TMAY-02207Alias QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU
Anti-NQO1 Antibody (2T646) is a Rabbit antibody targeting NQO1. Anti-NQO1 Antibody (2T646) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-NQO1 Antibody (2T646) is a Rabbit antibody targeting NQO1. Anti-NQO1 Antibody (2T646) can be used in WB. |
| Alias | QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2T646 |
| Reactivity | Human |
| Verified Activity | Anti-NQO1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: A549 Whole Cell Lysate. -Lane B: MCF7 Whole Cell Lysate. -Lane C: Raji Whole Cell Lysate. -Lane D: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size:31 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human NQO1 (rh NQO1; TMPY-03407; P15559-1; Met1-Lys274). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recent pharmacological research suggests the feasibility of genotype-directed redox chemotherapeutic intervention targeting NQO1 breast cancer, a common missense genotype encoding a functionally impaired NQO1 protein. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human NQO1 Protein (TMPY-03407) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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