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Bifikafusp alfa

Name: Bifikafusp alfa
Brand: TargetMol
SKU: T82887
Rating: 4.5 (1 reviews)

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Catalog No. T82887Cas No. 1957239-90-5

Alias L19-IL2

Bifikafusp alfa (L19-IL2) is an immunotherapeutic fusion protein combining human L19 antibodies with the cytokine interleukin 2 (IL2), targeting the extra domain B (EDB) of fibronectin, and has demonstrated anticancer activity [1].

Bifikafusp alfa

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Catalog No. T82887Alias L19-IL2Cas No. 1957239-90-5

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	Inquiry	Inquiry	Inquiry
5 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

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Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity

Description	Bifikafusp alfa (L19-IL2) is an immunotherapeutic fusion protein combining human L19 antibodies with the cytokine interleukin 2 (IL2), targeting the extra domain B (EDB) of fibronectin, and has demonstrated anticancer activity [1].
In vivo	Bifikafusp alfa (1.43 and 4.29 MIU/kg; i.p.; daily; for 10 days; female NMRI nude mice MiaPaca-A2 xenografts) exhibited antitumor activity against established pancreatic cancer [1].
Synonyms	L19-IL2
Reactivity	Human
Application	ELISA FACS Functional assay
Antibody Type	Monoclonal
Endotoxin	＜ 1.0 EU/mg

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Target

EDB

Chemical Properties

Cas No.

1957239-90-5

Storage & Solubility Information

Storage

-20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

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