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Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody

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Catalog No. TMAC-04094

Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-MPL (Tyr626). Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody can be used in WB.

Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody

Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody

😃Good
Catalog No. TMAC-04094
Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-MPL (Tyr626). Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-MPL (Tyr626). Anti-Phospho-C-MPL (Tyr626) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundMPL proto-oncogene, thrombopoietin receptor(MPL) Homo sapiens In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human TPOR around the phosphorylation site of Tyr626
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 69, 40 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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