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Anti-G-CSF Antibody (9P968) (Synonyms: MGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte))

Catalog No. TMAY-00050 Copy Product Info
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Anti-G-CSF Antibody (9P968) is a Rabbit antibody targeting G-CSF. Anti-G-CSF Antibody (9P968) can be used in ELISA(Det).

Anti-G-CSF Antibody (9P968)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00050
Synonyms MGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte)

Anti-G-CSF Antibody (9P968) is a Rabbit antibody targeting G-CSF. Anti-G-CSF Antibody (9P968) can be used in ELISA(Det).

Anti-G-CSF Antibody
(9P968)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$927-10 days7-10 days
100 μL$2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-G-CSF Antibody (9P968) is a Rabbit antibody targeting G-CSF. Anti-G-CSF Antibody (9P968) can be used in ELISA(Det).
SynonymsMGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte)
Ig Type
Rabbit IgG
Clone
9P968
Reactivity
Human
Specificity
Human G-CSF
Application
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human G-CSF/CSF3 (rh G-CSF/CSF3; NP_757373.1Ala30-Pro204).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGranulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial cells. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. Recent animal studies have also revealed that G-CSF activates multiple signaling pathways, such as Akt and also the Janus family kinase-2 and signal transducer and activation of transcription-3 (Jak2-STAT3) pathway, thereby promoting survival, proliferation, differentiation and mobilisation of haematopoietic stem and progenitor cells. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. G-CSF prevents left ventricular remodeling after myocardial infarction by decreasing cardiomyocyte death and by increasing the number of blood vessels, suggesting the importance of direct actions of G-CSF on the myocardium rather than through mobilization and differentiation of stem cells. Accordingly, recombinant human (rh)G-CSF has been extensively used in clinical haematology and oncology to enable bone marrow transplantation or to treat chemotherapy-associated neutropenia. In preclinical study, G-CSF improved cardiac function and perfusion by angiomyogenesis and protection of cardiomyocytes in myocardial infarction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human G-CSF/CSF3 Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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