SARS-CoV-IN-1

Name: SARS-CoV-IN-1
Brand: TargetMol
SKU: T12837
Rating: 4.5 (1 reviews)

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Catalog No. T12837Cas No. 888958-25-6

SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor with an EC50 of 4.9 μM in Vero cells.

SARS-CoV-IN-1

😃Good

Catalog No. T12837Cas No. 888958-25-6

SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor with an EC50 of 4.9 μM in Vero cells.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,780	6-8 weeks	6-8 weeks
50 mg	$2,320	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly

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Product Introduction

Bioactivity

Description	SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor with an EC50 of 4.9 μM in Vero cells.
Targets&IC50	P. falciparum (W2):133.2 nM , P. falciparum (W2):459.1 nM, SARS-CoV (Vero cells):4.9 μM(EC50) , P. falciparum (3D7):15.4 nM , P. falciparum (3D7):IC90: 25.7 nM
In vitro	In vitro growth of Plasmodium falciparum inhibited by SARS-CoV-IN-1 far better than Chloroquine (CQ) .

Chemical Properties

Molecular Weight	449.76
Formula	C₂₃H₂₄ClFeN₃O
Cas No.	888958-25-6
Smiles	C(NC=1C2=C(N=CC1)C=C(Cl)C=C2)[C-]34[Fe+2]56789%10%11(C3(CNCCO)=[CH]5[CH]6=[CH]74)[CH-]%12[CH]8=[CH]9[CH]%10=[CH]%11%12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc