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H-Tyr-Phe-OH (Synonyms: L-Tyrosyl-L-phenylalanine)

Catalog No. T60935 Copy Product Info
Purity: 99.46%
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H-Tyr-Phe-OH(L-Tyrosyl-L-phenylalanine) is a dipeptide/polypeptide composed of tyrosine and phenylalanine that inhibits the activity of the angiotensin-converting enzyme (ACE) and has oral activity. It can be used as a biomarker for the study of thyroid nodules and also exhibits xanthine oxidase inhibitory (uric acid lowering) activity and acts as a regulator of IL-8 production by neutrophil-like cells.

H-Tyr-Phe-OH

Copy Product Info
🥰Excellent
Catalog No. T60935
Synonyms L-Tyrosyl-L-phenylalanine

H-Tyr-Phe-OH(L-Tyrosyl-L-phenylalanine) is a dipeptide/polypeptide composed of tyrosine and phenylalanine that inhibits the activity of the angiotensin-converting enzyme (ACE) and has oral activity. It can be used as a biomarker for the study of thyroid nodules and also exhibits xanthine oxidase inhibitory (uric acid lowering) activity and acts as a regulator of IL-8 production by neutrophil-like cells.

H-Tyr-Phe-OH
Cas No. 17355-11-2
Pack SizePriceUSA StockGlobal StockQuantity
25 mg$497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.46%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
H-Tyr-Phe-OH(L-Tyrosyl-L-phenylalanine) is a dipeptide/polypeptide composed of tyrosine and phenylalanine that inhibits the activity of the angiotensin-converting enzyme (ACE) and has oral activity. It can be used as a biomarker for the study of thyroid nodules and also exhibits xanthine oxidase inhibitory (uric acid lowering) activity and acts as a regulator of IL-8 production by neutrophil-like cells.
SynonymsL-Tyrosyl-L-phenylalanine
Chemical Properties
Molecular Weight328.36
FormulaC18H20N2O4
Cas No.17355-11-2
SmilesC([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)N)C2=CC=C(O)C=C2
SequenceH-Tyr-Phe-OH
Sequence ShortYF
Storage & Solubility Information
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2 mg/mL (6.09 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0454 mL15.2272 mL30.4544 mL152.2719 mL
5 mM0.6091 mL3.0454 mL6.0909 mL30.4544 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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