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Anti-CD204/MSR1 Polyclonal Antibody

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Catalog No. TMAB-00345

Anti-CD204/MSR1 Polyclonal Antibody is a Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Polyclonal Antibody can be used in WB.

Anti-CD204/MSR1 Polyclonal Antibody

Anti-CD204/MSR1 Polyclonal Antibody

😃Good
Catalog No. TMAB-00345
Anti-CD204/MSR1 Polyclonal Antibody is a Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$372 7-10 days
200 μL$529 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD204/MSR1 Polyclonal Antibody is a Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat
Verified Activity
Sample:
Lane 1: Spleen (Mouse) Lysate at 40 μg
Lane 2: Lung (Mouse) Lysate at 40 μg
Lane 3: Liver (Mouse) Lysate at 40 μg
Lane 4: Placenta (Mouse) Lysate at 40 μg
Lane 5: Cerebrum (Mouse) Lysate at 40 μg
Lane 6: Raw264.7 (Mouse) Cell Lysate at 30 μg
Lane 7: NIH/3T3 (Mouse) Cell Lysate at 30 μg
Lane 8: Liver (Rat) Lysate at 40 μg
Lane 9: Cerebrum (Rat) Lysate at 40 μg
Primary: Anti-MSR1 (TMAB-00345) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50/39 kDa
Observed band size: 50 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type II membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MSR1/CD204
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Heart disease,Lipoprotein metabolism,Macrophage / Inflamm.,Innate and adaptive immunity,Lipoprotein metabolism
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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