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6α-hydroxy Paclitaxel

Name: 6α-hydroxy Paclitaxel
Brand: TargetMol
SKU: T36896
Rating: 4.5 (1 reviews)

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Catalog No. T36896Cas No. 153212-75-0

Alias 6alpha-hydroxypaclitaxel

6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.

6α-hydroxy Paclitaxel

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Purity: 99.33%

Catalog No. T36896Alias 6alpha-hydroxypaclitaxelCas No. 153212-75-0

6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.

Pack Size	Price	USA Warehouse	Global Warehouse
500 μg	$592	35 days	35 days
1 mg	$850	-	In Stock
5 mg	$3,920	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.33%

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COA

Product Introduction

Bioactivity

Description	6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.
Targets&IC50	WRL6 cells:213.6 μg/mL, H1299 cells:94.48 μg/mL
Synonyms	6alpha-hydroxypaclitaxel

Chemical Properties

Molecular Weight	869.91
Formula	C₄₇H₅₁NO₁₅
Cas No.	153212-75-0
Smiles	[H][C@]12OC[C@@]1(OC(C)=O)[C@@]1([H])[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]1(C)[C@@H](O)[C@@H]2O)C3(C)C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: 10 mg/mL (11.5 mM), Sonication is recommended.

DMSO: 10 mg/mL (11.50 mM), Sonication is recommended.

Solution Preparation Table

Methanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1495 mL	5.7477 mL	11.4954 mL	57.4772 mL
5 mM	0.2299 mL	1.1495 mL	2.2991 mL	11.4954 mL
10 mM	0.1150 mL	0.5748 mL	1.1495 mL	5.7477 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc