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Anti-MRP2 Antibody (3L876)

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Catalog No. TMAC-02648
Alias multidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30

Anti-MRP2 Antibody (3L876) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3L876) can be used in WB,ICC,IHC,FCM.

Anti-MRP2 Antibody (3L876)

Anti-MRP2 Antibody (3L876)

😃Good
Catalog No. TMAC-02648Alias multidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30
Anti-MRP2 Antibody (3L876) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3L876) can be used in WB,ICC,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-MRP2 Antibody (3L876) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3L876) can be used in WB,ICC,IHC,FCM.
Synonymsmultidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
4. ICC staining MRP2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining MRP2 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of A549 cells with MRP2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
7. Western blot analysis of MRP2 on different lysates with MRP2 at 1/2,000 dilution. Lane 1: HepG2 cell lysate, Lane 2: A549 cell lysate, Lane 3: HeLa cell lysate (negative) Lysates/proteins at 15 ug/Lane. Predicted band size: 174 kDa, Observed band size: 300 kDa, Exposure time: 5 minutes; 4-20% SDS-PAGE gel.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMulti-drug resistance protein 2 (MRP2), also known as ABCC2, is an ATP binding cassette (ABC) transporter responsible for biliary excretion of xenobiotics, endobiotics, and their metabolites. Deficiency in ABCC2 results in the clinical disorder Dubin-Johnson syndrome. MRP2 is found to be expressed in a variety of human cancers, and is associated with resistance of tumor cells to various anticancer drugs including cisplatin. The predicted molecular weight of MRP2 is 174 kDa, while mature MRP2 usually has a slower migration around 190-250 kDa due to the glycosylation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 174 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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