GRO beta/CXCL2 Protein, Mouse, Recombinant

Name: GRO beta/CXCL2 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPJ-00011
Rating: 4.5 (1 reviews)

(Synonyms: SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2) Copy Product Info

Synonyms: SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2

Catalog No. TMPJ-00011 Copy Product Info

C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

GRO beta/CXCL2 Protein, Mouse, Recombinant

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P10889
Amino Acid	Ala28-Asn100
Construction	Ala28-Asn100
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2
Research Background	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

Chemical Properties

Molecular Weight

10 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.