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GRO beta/CXCL2 Protein, Mouse, Recombinant
(Synonyms: SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2) Copy Product InfoSynonyms: SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2
Catalog No. TMPJ-00011 Copy Product Info
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 7-10 days | 7-10 days | |
| 10 μg | $183 | 7-10 days | 7-10 days | |
| 20 μg | $292 | 7-10 days | 7-10 days | |
| 50 μg | $545 | 7-10 days | 7-10 days | |
| 100 μg | $792 | 7-10 days | 7-10 days | |
| 200 μg | $1,150 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Storage & Solubility Information
| Description | C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P10889 |
| Amino Acid | Ala28-Asn100 |
| Construction | Ala28-Asn100 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | SCYB2, MIP2-α, MIP2-alpha, MIP2A, MIP-2, MGSA-β, MGSA-beta, MGSA-b, melanoma growth stimulatory activity β, melanoma growth stimulatory activity beta, Macrophage Inflammatory Protein-2-α, Macrophage Inflammatory Protein-2-alpha, Gro-β, Growth-regulated protein β, Growth-regulated protein beta, Gro-beta, GROB, GRO2, GRO β, GRO beta, cxcl2, C-X-C motif chemokine 2, chemokine ligand 2 |
| Research Background |
| Molecular Weight | 10 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: GRO beta/CXCL2 Protein, Mouse, Recombinant chemical structure | GRO beta/CXCL2 Protein, Mouse, Recombinant molecular weight
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