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Hydrocortisone buteprate

Name: Hydrocortisone buteprate
Brand: TargetMol
SKU: T13728
Price: 69 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T13728Cas No. 72590-77-3

Alias Hydrocortisone probutate, HBP

Hydrocortisone buteprate is a medium-potent, non-halogenated double-ester derivative of hydrocortisone that has researches indicate highly favorable benefit-to-risk ratio in inflammatory dermatological disorders.

Hydrocortisone buteprate

🥰Excellent

Catalog No. T13728Alias Hydrocortisone probutate, HBPCas No. 72590-77-3

Pack Size	Price	Availability
5 mg	$49	In Stock
10 mg	Preferential	In Stock
25 mg	Preferential	In Stock
1 mL x 10 mM (in DMSO)	$69	In Stock

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Product Introduction

Bioactivity

Description	Hydrocortisone buteprate is a medium-potent, non-halogenated double-ester derivative of hydrocortisone that has researches indicate highly favorable benefit-to-risk ratio in inflammatory dermatological disorders.
Synonyms	Hydrocortisone probutate, HBP

Chemical Properties

Molecular Weight	488.61
Formula	C₂₈H₄₀O₇
Cas No.	72590-77-3
Smiles	C(COC(CC)=O)(=O)[C@]1(OC(CCC)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])[H]
Relative Density.	1.20 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (409.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0466 mL	10.2331 mL	20.4662 mL	102.3311 mL
5 mM	0.4093 mL	2.0466 mL	4.0932 mL	20.4662 mL
10 mM	0.2047 mL	1.0233 mL	2.0466 mL	10.2331 mL
20 mM	0.1023 mL	0.5117 mL	1.0233 mL	5.1166 mL
50 mM	0.0409 mL	0.2047 mL	0.4093 mL	2.0466 mL
100 mM	0.0205 mL	0.1023 mL	0.2047 mL	1.0233 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Hydrocortisone buteprate