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14-Deoxyandrographolide

Name: 14-Deoxyandrographolide
Brand: TargetMol
SKU: T8288
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T8288Cas No. 4176-97-0

14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.

14-Deoxyandrographolide

🥰Excellent

Purity: 99.89%

Catalog No. T8288Cas No. 4176-97-0

Pack Size	Price	Availability
1 mg	$56	In Stock
5 mg	$147	In Stock
10 mg	$228	In Stock
25 mg	$389	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	334.45
Formula	C₂₀H₃₀O₄
Cas No.	4176-97-0
Smiles	[H][C@]12CCC(=C)[C@@H](CCC3=CCOC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO
Relative Density.	1.15g/cm3
Color	White
Appearance	solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 3.34 mg/mL (9.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9900 mL	14.9499 mL	29.8998 mL	149.4992 mL
5 mM	0.5980 mL	2.9900 mL	5.9800 mL	29.8998 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc