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Anti-IRE1 Polyclonal Antibody
(Synonyms: IRE1P, IRE1a, IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1) Copy Product Info
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Synonyms: IRE1P, IRE1a, IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1
Catalog No. TMAB-00982 Copy Product Info
🥰Excellent
Anti-IRE1 Polyclonal Antibody is a Rabbit antibody targeting IRE1. Anti-IRE1 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Anti-IRE1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-IRE1 Polyclonal Antibody is a Rabbit antibody targeting IRE1. Anti-IRE1 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | IRE1P, IRE1a, IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1 |
| Ig Type | IgG |
| Reactivity | Mouse,Pig (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Ubiquitously expressed. High levels observed in pancreatic tissue. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Immunogen | KLH conjugated synthetic peptide: human IRE1 |
| Antigen Species | Human |
| Gene Name | ERN1 |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase/endoribonuclease IRE1 |
| Uniprot ID | |
| Biology Area | Other Kinases |
| Function | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Molecular Weight | Theoretical: 105 kDa. Actual: 105 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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