Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-IL-3R alpha/CD123 Antibody (6U879) (Synonyms: interleukin 3 receptor, α (low affinity), interleukin 3 rece...)
Catalog No. TMAY-03474 Copy Product Info
🥰Excellent
Anti-IL-3R alpha/CD123 Antibody (6U879) is a Rabbit antibody targeting IL-3R alpha/CD123. Anti-IL-3R alpha/CD123 Antibody (6U879) can be used in ELISA.
Anti-IL-3R alpha/CD123 Antibody (6U879)
Copy Product Info🥰Excellent
Catalog No. TMAY-03474
Synonyms interleukin 3 receptor, α (low affinity), interleukin 3 receptor, alpha (low affinity), IL3RY, IL3RX, IL3RAY, IL-3R α/CD123, IL3R, hIL-3Ra, CD123
Anti-IL-3R alpha/CD123 Antibody (6U879) is a Rabbit antibody targeting IL-3R alpha/CD123. Anti-IL-3R alpha/CD123 Antibody (6U879) can be used in ELISA.
Anti-IL-3R alpha/CD123 Antibody
(6U879)
(6U879)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-3R alpha/CD123 Antibody (6U879) is a Rabbit antibody targeting IL-3R alpha/CD123. Anti-IL-3R alpha/CD123 Antibody (6U879) can be used in ELISA. |
| Synonyms | interleukin 3 receptor, α (low affinity), interleukin 3 receptor, alpha (low affinity), IL3RY, IL3RX, IL3RAY, IL-3R α/CD123, IL3R, hIL-3Ra, CD123 |
| Ig Type | Rabbit IgG |
| Clone | 6U879 |
| Reactivity | Mouse |
| Specificity | Mouse IL-3R alpha/CD123 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL3Ra (rM IL3Ra; TMPY-00592; Met1-Lys331; EDL20630.1) . |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subfamily. The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. The WSXWS motif of IL3RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box one motif of IL3RA is required for JAK interaction and/or activation. IL3RA represents a unique marker for primitive leukemic stem cells. Targeting of IL3RA may be a promising strategy for the preferential ablation of AML cells. Aberrant IL3RA expression is a good marker for monitoring of minimal residual disease. IL3RA is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. Recent studies have shown that interleukin-3 receptor alpha (CD123) is highly expressed on leukemia stem cells of patients with acute myeloid leukemia, and is correlated with tumor load and poor prognosis. CD123 was highly expressed in the bone marrow of the patients with myelodysplastic syndrome (MDS), significantly correlated with the proportion of bone marrow blasts, and thus might be the marker of MDS malignant clone. IL3RA is also a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes as its expression is characteristic of typical hairy cell leukemia (HCL) with high sensitivity and specificity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse IL3Ra protein (TMPY-00592) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-IL-3R alpha/CD123 Antibody (6U879) | purchase Anti-IL-3R alpha/CD123 Antibody (6U879) | Anti-IL-3R alpha/CD123 Antibody (6U879) cost | order Anti-IL-3R alpha/CD123 Antibody (6U879)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.