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IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP) Copy Product Info

Synonyms: IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP

Catalog No. TMPK-00326 Copy Product Info
IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$917-10 days7-10 days
10 µg$1487-10 days7-10 days
20 µg$2457-10 days7-10 days
50 µg$4837-10 days7-10 days
100 µg$8137-10 days7-10 days
200 µg$1,4707-10 days7-10 days
500 µg$3,2507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Anti-IFNAR1 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IFNAR1, His Tag with the EC50 of 1.7ng/ml determined by ELISA.
Description
IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP17181-1
ConstructionLys28-Lys436
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsIFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP
Research Background
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Chemical Properties
Molecular Weight50.2 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight