Shopping Cart
Remove All
Your shopping cart is currently empty
Sulfobromophthalein disodium salt
Copy Product Info
🥰Excellent
Catalog No. TD0105Cas No. 71-67-0
Sulfobromophthalein disodium salt is an organic anion dye, it is used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites.
Sulfobromophthalein disodium salt
Copy Product Info🥰Excellent
Purity: 97.16%
Catalog No. TD0105Cas No. 71-67-0
Sulfobromophthalein disodium salt is an organic anion dye, it is used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $30 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:97.16%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Sulfobromophthalein disodium salt AI Summary
Sulfobromophthalein disodium salt demonstrates bioactivity across multiple transportation assays involving various cell types and transporters. It shows activity in human MRP2-mediated estradiol-17-beta-glucuronide transport in Sf9 cells with 5.0% activity relative to control. In OATP-C-expressing HEK293 cells, it has a Km value of 140.0 nM. Importantly, Sulfobromophthalein disodium salt acts as both a substrate and an inhibitor in various systems, including Xenopus laevis oocytes and HeLa cells, with Km values ranging from 300.0 nM to 20000.0 nM and Ki values up to 144000.0 nM. The compound shows significant inhibition of several transporters such as OATP1B1, OATP1B3, and OATP2B1, with inhibition rates of up to 94.1%. Additionally, it impacts the permeability and efflux ratio in MRP2 knockdown human Caco2 cells and exhibits potential in blocking Ebola virus entry, highlighted by AC50 values in different screening channels. Overall, Sulfobromophthalein disodium salt is a multifaceted compound with diverse bioactivities influencing various transport mechanisms and displaying potential antiviral properties..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sulfobromophthalein disodium salt is an organic anion dye, it is used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites. |
| In vitro | I. Membrane carrier research 1. Solution preparation: Dissolve Bromosulfophthalein disodium salt in an appropriate solvent (such as saline). 2. Labeling process: By injecting a certain concentration of Bromosulfophthalein into experimental animals, researchers can track its metabolic pathways in the body and its distribution in different tissues. 3. Detection: Use a spectrophotometer or fluorescence microscope to measure the absorbance or fluorescence intensity of Sulfobromophthalein (depending on the experimental design) to analyze the function of the membrane carrier. II. Liver function test 1. Injection: Inject Sulfobromophthalein solution into experimental animals (such as rats), and the dosage depends on the experimental needs. 2. Monitoring: By detecting changes in Bromosulfophthalein concentration in plasma, the liver's uptake and excretion capacity can be inferred, and then the liver health can be evaluated. III. Drug metabolism research 1. Drug uptake: Inject drugs and Sulfobromophthalein into experimental animals, and use dyes as markers to track the drug transport process. 2. Monitoring: By monitoring the distribution and changes of Bromosulfophthalein in the body, the important carriers and mechanisms in the drug transport process can be studied. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands. |
| Molecular Weight | 838 |
| Formula | C20H8Br4Na2O10S2 |
| Cas No. | 71-67-0 |
| Smiles | O=C1OC(C2=CC(S(=O)([O-])=O)=C(O)C=C2)(C3=CC(S(=O)([O-])=O)=C(O)C=C3)C4=C1C(Br)=C(Br)C(Br)=C4Br.[Na+].[Na+] |
| Relative Density. | no data available |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 490 mg/mL (584.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (5.97 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Sulfobromophthalein disodium salt | purchase Sulfobromophthalein disodium salt | Sulfobromophthalein disodium salt cost | order Sulfobromophthalein disodium salt | Sulfobromophthalein disodium salt chemical structure | Sulfobromophthalein disodium salt in vitro | Sulfobromophthalein disodium salt formula | Sulfobromophthalein disodium salt molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.