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2,3-dinor-11β-Prostaglandin F2α

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Catalog No. T37275Cas No. 240405-20-3
Alias 2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α when measured using 's 11β-PGF2α EIA Kit . The excretion rate for 2,3-dinor-11β-PGF2α is approximately 200-250 ng/24 hours in a normal adult.

2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α

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Catalog No. T37275Alias 2,3-dinor-11β-Prostaglandin F2αCas No. 240405-20-3
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α when measured using 's 11β-PGF2α EIA Kit . The excretion rate for 2,3-dinor-11β-PGF2α is approximately 200-250 ng/24 hours in a normal adult.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μg$28935 days35 days
50 μg$55435 days35 days
100 μg$1,02635 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α when measured using 's 11β-PGF2α EIA Kit . The excretion rate for 2,3-dinor-11β-PGF2α is approximately 200-250 ng/24 hours in a normal adult.
Synonyms2,3-dinor-11β-Prostaglandin F2α
Chemical Properties
Molecular Weight326.43
FormulaC18H30O5
Cas No.240405-20-3
SmilesC(/C=C\CC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@@H](O)C[C@@H]1O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 10 mg/mL (30.63 mM), Sonication is recommended.
DMF: 100 mg/mL (306.34 mM), Sonication is recommended.
Ethanol: 100 mg/mL (306.34 mM), Sonication is recommended.
DMSO: 100 mg/mL (306.34 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMF/Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.0634 mL15.3172 mL30.6344 mL153.1722 mL
5 mM0.6127 mL3.0634 mL6.1269 mL30.6344 mL
10 mM0.3063 mL1.5317 mL3.0634 mL15.3172 mL
20 mM0.1532 mL0.7659 mL1.5317 mL7.6586 mL
DMF/Ethanol/DMSO
1mg5mg10mg50mg
50 mM0.0613 mL0.3063 mL0.6127 mL3.0634 mL
100 mM0.0306 mL0.1532 mL0.3063 mL1.5317 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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