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Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) is a HRP-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $293 | 7-10 days | 7-10 days |
| Description | Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) is a HRP-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-HRP (3X829) can be used in ELISA. |
| Synonyms | transferrin receptor |
| Ig Type | Mouse IgG1 |
| Clone | 3X829 |
| Reactivity | Human |
| Specificity | Human Transferrin Receptor/TFR1/CD71 |
| Application | |
| Recommended Dose | ELISA: 0.1-1 μg/mL |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe 760). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human Transferrin Receptor / TFRC / CD71 protein (TMPY-01873) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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