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Anti-Syntrophin alpha 1 Antibody (6T145)
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Catalog No. TMAC-03946
Alias TACIP1, Syntrophinα1, Syntrophinalpha1, Syntrophina1, Syntrophin-1, Syntrophin α 1, Syntrophin a 1, Syntrophin 1, SNTA1_HUMAN, Snta1, SNT1, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, OTTHUMP00000030650, LQT12, Dystrophin associated protein A1 59kDa acidic component, dJ1187J4.5, Alpha-1-syntrophin, Alpha 1 syntrophin, Acidic alpha 1 syntrophin, 59 kDa dystrophin-associated protein A1 acidic component 1
Anti-Syntrophin alpha 1 Antibody (6T145) is a Rabbit antibody targeting Syntrophin alpha 1. Anti-Syntrophin alpha 1 Antibody (6T145) can be used in WB,ICC,IF,IHC,FCM.
Anti-Syntrophin alpha 1 Antibody (6T145)
Anti-Syntrophin alpha 1 Antibody (6T145)
😃Good
Catalog No. TMAC-03946Alias TACIP1, Syntrophinα1, Syntrophinalpha1, Syntrophina1, Syntrophin-1, Syntrophin α 1, Syntrophin a 1, Syntrophin 1, SNTA1_HUMAN, Snta1, SNT1, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, OTTHUMP00000030650, LQT12, Dystrophin associated protein A1 59kDa acidic component, dJ1187J4.5, Alpha-1-syntrophin, Alpha 1 syntrophin, Acidic alpha 1 syntrophin, 59 kDa dystrophin-associated protein A1 acidic component 1
Anti-Syntrophin alpha 1 Antibody (6T145) is a Rabbit antibody targeting Syntrophin alpha 1. Anti-Syntrophin alpha 1 Antibody (6T145) can be used in WB,ICC,IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Syntrophin alpha 1 Antibody (6T145) is a Rabbit antibody targeting Syntrophin alpha 1. Anti-Syntrophin alpha 1 Antibody (6T145) can be used in WB,ICC,IF,IHC,FCM. |
| Synonyms | TACIP1, Syntrophinα1, Syntrophinalpha1, Syntrophina1, Syntrophin-1, Syntrophin α 1, Syntrophin a 1, Syntrophin 1, SNTA1_HUMAN, Snta1, SNT1, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, OTTHUMP00000030650, LQT12, Dystrophin associated protein A1 59kDa acidic component, dJ1187J4.5, Alpha-1-syntrophin, Alpha 1 syntrophin, Acidic alpha 1 syntrophin, 59 kDa dystrophin-associated protein A1 acidic component 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of Syntrophin alpha 1 on SiHa cells lysates using anti-Syntrophin alpha 1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using anti-Syntrophin alpha 1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Syntrophin alpha 1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Syntrophin alpha 1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Syntrophin alpha 1 antibody. Counter stained with hematoxylin. 6. ICC staining Syntrophin alpha 1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining Syntrophin alpha 1 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. ICC staining Syntrophin alpha 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 9. Flow cytometric analysis of LOVO cells with Syntrophin alpha 1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The syntrophins are PDZ-domain-containing proteins that facilitate the recruitment of signaling proteins such as NOS1 to the dystrophin-associated protein complex. The syntrophin family are structurally related proteins that contain multiple protein interaction motifs. Syntrophins associate directly with dystrophin, the product of the Duchenne muscular dystrophy locus, and its homologs. α-Syntrophin has an important role in synapse formation and in the organization of utrophin, acetylcholine receptor and acetylcholinester-ase at the neuromuscular synapse. Specifically, NOS1 binds to α-Syntrophin at muscle sarcolemma. β2-Syntrophin is a modular adapter. In muscle cells, β2-Syntrophin interacts with members of the dystrophin family, which in-cludes utrophin. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human Syntrophin alpha 1 aa 1-200 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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