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Neurotrophin 3 Protein, Human, Recombinant

Catalog No. TMPY-04069
Synonyms: NGF2, HDNF, NT-3, neurotrophin 3, NGF-2, NT3

NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Neurotrophin 3 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
20 μg In stock $ 177.00
100 μg 5 days $ 397.00
200 μg 5 days $ 679.00
500 μg 5 days $ 2,140.00
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Biological Description
Technical Params
Product Properties
Biological Information Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2 μg/ml (100 μl/well) can bind human TrkB-Fch . The EC50 of human TrkB-Fch is 120-350 ng/mL.

Description NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.
Species Human
Expression System E. coli
Tag Tag Free
Accession Number P20783-1
Synonyms NGF2, HDNF, NT-3, neurotrophin 3, NGF-2, NT3
Construction A DNA sequence encoding the human NT3 (P20783-1) (Tyr139-Thr257) was expressed and purified.
Protein Purity > 90 % as determined by SDS-PAGE

Molecular Weight Approxiamtely 13.8 kDa
Endotoxin Please contact us for more information.
Formulation Lyophilized from sterile PBS, pH 5. 2. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.

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Keywords

Neurotrophin 3 Protein, Human, Recombinant NGF 2 NGF2 HDNF NT-3 neurotrophin 3 NGF-2 NT 3 NT3 recombinant recombinant-proteins proteins protein

 

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