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Kaempferol 3,7,4'-trimethyl ether

🥰Excellent
Catalog No. TN1817Cas No. 15486-34-7
Alias Kaempferol 3,7,4'-trimethylether

Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) demonstrates selective cytotoxic activities against nine tested cancer cell lines.

Kaempferol 3,7,4'-trimethyl ether

Kaempferol 3,7,4'-trimethyl ether

🥰Excellent
Purity: 99.98%
Catalog No. TN1817Alias Kaempferol 3,7,4'-trimethyletherCas No. 15486-34-7
Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) demonstrates selective cytotoxic activities against nine tested cancer cell lines.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$30In StockIn Stock
5 mg$68In StockIn Stock
10 mg$106In StockIn Stock
25 mgPreferentialIn StockIn Stock
50 mgPreferentialIn StockIn Stock
1 mL x 10 mM (in DMSO)$77In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.98%
Appearance:Solid
Color:Yellow
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) demonstrates selective cytotoxic activities against nine tested cancer cell lines.
In vitro
The IC50 values below or around 30 μg/mL were recorded with A. arundinaceum extract against eight of the nine tested cancer cell lines. This extract displayed IC50 values below 40 μg/mL towards the nine tested cancer cell lines whilst A. polyanthum extract, Kaempferol 3,7,4'-trimethylether showed selective activities. Collateral sensitivity (hypersensitivity) was observed with A. arundinaceum extract towards leukemia CEM/ADR5000 cells and glioblastoma U87MG.ΔEGFR compared to their respective sensitive counterparts CEM/CEM and U87MG.[1]
SynonymsKaempferol 3,7,4'-trimethylether
Chemical Properties
Molecular Weight328.32
FormulaC18H16O6
Cas No.15486-34-7
SmilesCOc1ccc(cc1)-c1oc2cc(OC)cc(O)c2c(=O)c1OC
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 11 mg/mL (33.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0458 mL15.2290 mL30.4581 mL152.2904 mL
5 mM0.6092 mL3.0458 mL6.0916 mL30.4581 mL
10 mM0.3046 mL1.5229 mL3.0458 mL15.2290 mL
20 mM0.1523 mL0.7615 mL1.5229 mL7.6145 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NOSynthaseNO SynthaseKaempferol 3,7,4'-trimethyl etherKaempferol 3,7,4'trimethyl etherKaempferol 3,7,4' trimethyl etherInhibitorinhibit
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