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Meprednisone (Synonyms: SCH 4358, NSC 527579, Methylprednisone, Betapar, Betanisona)

Name: Meprednisone
Brand: TargetMol
SKU: T6580
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T6580 Copy Product Info

Purity: 98.80%

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Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.

Meprednisone

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Catalog No. T6580

Synonyms SCH 4358, NSC 527579, Methylprednisone, Betapar, Betanisona

Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.

Cas No. 1247-42-3

Pack Size	Price	USA Stock	Global Stock
5 mg	$30	In Stock	In Stock
10 mg	$51	In Stock	In Stock
25 mg	$95	In Stock	In Stock
50 mg	$148	In Stock	In Stock
100 mg	$245	In Stock	In Stock
200 mg	$365	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.80%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Meprednisone AI Summary

Meprednisone shows inhibition against the MES-SA/DX5 cell line, as determined using a P-glycoprotein assay, with an activity result of 0.86. It demonstrates bioactivity in assays targeting the entry of Ebola virus, with AC50 values ranging from 8912.5 nM to 39.81 µM across different channels, indicating potential antiviral properties. Additionally, Meprednisone exhibits inhibitory activity on human HDAC6, with -3.64% inhibition in an enzymatic assay using a commercial peptide substrate and 7.54% inhibition using a custom peptide substrate..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.
Synonyms	SCH 4358, NSC 527579, Methylprednisone, Betapar, Betanisona

Chemical Properties

Molecular Weight	372.45
Formula	C₂₂H₂₈O₅
Cas No.	1247-42-3
Smiles	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@]2(C)[C@@]1(O)C(=O)CO
Relative Density.	1.28 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 50 mg/mL (134.25 mM), Sonication is recommended.

Ethanol: 4 mg/mL (10.74 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (6.71 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6849 mL	13.4246 mL	26.8492 mL	134.2462 mL
5 mM	0.5370 mL	2.6849 mL	5.3698 mL	26.8492 mL
10 mM	0.2685 mL	1.3425 mL	2.6849 mL	13.4246 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1342 mL	0.6712 mL	1.3425 mL	6.7123 mL
50 mM	0.0537 mL	0.2685 mL	0.5370 mL	2.6849 mL
100 mM	0.0268 mL	0.1342 mL	0.2685 mL	1.3425 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc