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Anti-TNF-alpha Antibody (1Q983)

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Catalog No. TMAY-01011

Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM.

Anti-TNF-alpha Antibody (1Q983)

Anti-TNF-alpha Antibody (1Q983)

😃Good
Catalog No. TMAY-01011
Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μL$2687-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM.
Ig Type
Rabbit IgG
Clone
1Q983
Reactivity
Human
Specificity
Human TNF-alpha
Verified Activity
Flow cytometric analysis of Human TNF-α expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human TNF-α, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-alpha / TNFA / TNFSF2 (rh TNF-alpha / TNFA / TNFSF2; TMPY-00936; NP_000585.2; Val77-Leu233).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human TNF-alpha / TNFA / TNFSF2 Protein (TMPY-00936)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tumor necrosis factor ligand superfamily member 1Tumor necrosis factorTNF-βTNFβTNF-αTNFαTNF-betaTNF-bTNF-alphaTNF-atnfaLymphotoxin-αLymphotoxinαLymphotoxin-alphaLymphotoxin-a
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