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Anti-TNF-alpha Antibody (1Q983)
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Catalog No. TMAY-01011
Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM.
Anti-TNF-alpha Antibody (1Q983)
Anti-TNF-alpha Antibody (1Q983)
😃Good
Catalog No. TMAY-01011
Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-TNF-alpha Antibody (1Q983) is a Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (1Q983) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1Q983 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human TNF-α expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human TNF-α, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-alpha / TNFA / TNFSF2 (rh TNF-alpha / TNFA / TNFSF2; TMPY-00936; NP_000585.2; Val77-Leu233). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human TNF-alpha / TNFA / TNFSF2 Protein (TMPY-00936) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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