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PSG9 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00522
Synonyms: PS-β-G-11, PS-β-G-9, PS-β-B, Pregnancy-specific β-1 glycoprotein B, Pregnancy-specific beta-1-glycoprotein 11, Pregnancy-specific β-1-glycoprotein 9, Pregnancy-specific glycoprotein, PS-beta-B, Pregnancy-specific β-1-glycoprotein 11, PSBG-11, PS34, PSBG-9, Pregnancy-specific glycoprotein 9, Pregnancy-specific beta-1 glycoprotein B, PS-beta-G-11, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9

Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
PSG9 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
Species Human
Expression System HEK293 Cells
Tag C-6xHis
Accession Number AAH20759.1
Synonyms PS-β-G-11, PS-β-G-9, PS-β-B, Pregnancy-specific β-1 glycoprotein B, Pregnancy-specific beta-1-glycoprotein 11, Pregnancy-specific β-1-glycoprotein 9, Pregnancy-specific glycoprotein, PS-beta-B, Pregnancy-specific β-1-glycoprotein 11, PSBG-11, PS34, PSBG-9, Pregnancy-specific glycoprotein 9, Pregnancy-specific beta-1 glycoprotein B, PS-beta-G-11, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9
Amino Acid Glu35-Ser426
Construction Glu35-Ser426
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 65 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.

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Keywords

PSG9 Protein, Human, Recombinant (His) PS-β-G-11 PS-b-G-9 PS-β-G-9 PS 34 PSBG 9 PS-β-B PS-b-G-11 Pregnancy-specific β-1 glycoprotein B PSBG 11 Pregnancy-specific beta-1-glycoprotein 11 Pregnancy-specific β-1-glycoprotein 9 PSBG11 Pregnancy-specific glycoprotein Pregnancy-specific b-1-glycoprotein 9 PS-beta-B Pregnancy-specific β-1-glycoprotein 11 PSBG-11 PS34 PSBG-9 PSBG9 PS-b-B PS-34 Pregnancy-specific b-1 glycoprotein B Pregnancy-specific glycoprotein 9 Pregnancy-specific b-1-glycoprotein 11 Pregnancy-specific beta-1 glycoprotein B PS-beta-G-11 Pregnancy-specific beta-1-glycoprotein 9 PS-beta-G-9 recombinant recombinant-proteins proteins protein

 

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