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Angiopoietin-1 Protein, Canine, Recombinant (His)

Catalog No. TMPH-00479
Synonyms: ANG-1, ANGPT1, Angiopoietin-1

Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is Q60FC1.

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Angiopoietin-1 Protein, Canine, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 491.00
100 μg 20 days $ 1,370.00
1 mg 20 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is Q60FC1.
Species Canine
Expression System Baculovirus Insect Cells
Tag C-6xHis
Accession Number Q60FC1
Synonyms ANG-1, ANGPT1, Angiopoietin-1
Amino Acid SNQRRSPENGGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVGPDFSSQKLQHLEHVMENYTQWLQKIENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEEWDTLKEERENLQVLVTRQTYIIQELEKQLNRATNNNSVLQKQQLELMDTVHNLVNLCTKEVLLKGGKKEEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYTLRIELMDCEGNRAYSQYDRFHIGNEKQNYRLYLKCHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDF
Construction 20-497 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 58.9 kDa (predicted)
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.

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Keywords

Angiopoietin-1 Protein, Canine, Recombinant (His) ANG-1 ANGPT1 Angiopoietin-1 recombinant recombinant-proteins proteins protein

 

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