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Anti-CXADR/CAR Antibody (8A220) (Synonyms: HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR)

Catalog No. TMAY-03034 Copy Product Info
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Anti-CXADR/CAR Antibody (8A220) is a Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody (8A220) can be used in ELISA,IHC-P.

Anti-CXADR/CAR Antibody (8A220)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03034
Synonyms HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR

Anti-CXADR/CAR Antibody (8A220) is a Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody (8A220) can be used in ELISA,IHC-P.

Anti-CXADR/CAR Antibody
(8A220)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CXADR/CAR Antibody (8A220) is a Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody (8A220) can be used in ELISA,IHC-P.
SynonymsHCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR
Ig Type
Rabbit IgG
Clone
8A220
Reactivity
Mouse
Specificity
Mouse CXADR/CAR
Has cross-reactivity in ELISA with
Human CXADR
Verified Activity
1. Immunochemical staining of mouse CXADR in mouse stomach with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of mouse CXADR in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CXADR (rM CXADR; TMPY-01939; NP_001020363.1; Met1-Gly237).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse CXADR protein (TMPY-01939)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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