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Anti-CXADR/CAR Antibody (8A220)
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Catalog No. TMAY-03034
Alias HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR
Anti-CXADR/CAR Antibody (8A220) is a Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody (8A220) can be used in ELISA,IHC-P.
Anti-CXADR/CAR Antibody (8A220)
Anti-CXADR/CAR Antibody (8A220)
😃Good
Catalog No. TMAY-03034Alias HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR
Anti-CXADR/CAR Antibody (8A220) is a Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody (8A220) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, IHC-P Reactivity: Mouse |
| Alias | HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR |
| Ig Type | Rabbit IgG |
| Clone | 8A220 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse CXADR in mouse stomach with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse CXADR in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CXADR (rM CXADR; TMPY-01939; NP_001020363.1; Met1-Gly237). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CXADR protein (TMPY-01939) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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